Which vaccine is contraindicated in pregnancy?

Live attenuated vaccines are contraindicated in pregnancy primarily because they contain live forms of the virus or bacteria that have the potential to cause disease, which could pose a risk to both the mother and the developing fetus. During pregnancy, the immune system is altered, making it more susceptible to infections, and the introduction of a live pathogen could lead to complications or sickness in the mother or impact fetal development.

In contrast, the inactivated flu vaccine, TDAP vaccine, and pneumococcal vaccine do not contain live pathogens and are generally considered safe for administration during pregnancy. The inactivated flu vaccine is recommended to protect both the mother and the newborn from influenza. The TDAP vaccine is important for protecting against tetanus, diphtheria, and pertussis, particularly during the third trimester to provide passive immunity to the infant. The pneumococcal vaccine, especially in certain high-risk populations, is also recommended to prevent pneumonia and serious infections.

These considerations highlight the critical importance of vaccine safety in protecting maternal and fetal health during pregnancy.