What class of medications is first-line for treating asthma in children?

Inhaled corticosteroids are considered the first-line treatment for asthma in children. This class of medications works by reducing inflammation in the airways, thereby improving breathing and decreasing the frequency of asthma exacerbations. They are effective in managing chronic asthma symptoms and are typically well-tolerated in pediatric patients.

Inhaled corticosteroids have a favorable safety profile compared to systemic corticosteroids, which can have significant side effects, especially with long-term use. Additionally, they provide targeted therapy directly to the lungs, minimizing systemic absorption and associated complications.

The other classes of medications mentioned can play important roles in a comprehensive asthma management plan but are not first-line treatments specifically for children with asthma. For instance, while leukotriene receptor antagonists are useful for some children and serve as an alternative, they do not possess the same potency for long-term control as inhaled corticosteroids. Long-acting beta-agonists may also be used, but they are generally recommended as an add-on therapy rather than as primary agents, particularly in pediatric populations. Oral corticosteroids are typically reserved for short courses during acute exacerbations or severe cases due to their side effects.