Which treatment is indicated for managing hypercalcemia?

Managing hypercalcemia effectively requires addressing the underlying volume status and restoring hydration, which is best accomplished with intravenous (IV) fluids. Isotonic saline helps to dilute serum calcium levels and promote renal excretion of calcium, effectively reducing hypercalcemia.

In cases where the patient is volume depleted, initiating IV fluids is particularly crucial, as dehydration can exacerbate hypercalcemia. By rehydrating the patient, the kidneys can function more effectively, filtering and excreting excess calcium from the body. This approach not only helps in lowering calcium levels but also restores electrolyte balance and hydration status.

Other options are not appropriate for managing hypercalcemia. Oral calcium supplements would increase calcium levels further, beta-blockers do not have a direct role in hypercalcemia management, and strict bed rest does not address the underlying issue of calcium excess. Therefore, the administration of IV isotonic saline is the correct approach for effectively managing hypercalcemia.